Table MTT4. t-test (ANOVA) for difference of means in 2×2 crossover design

See nQuery Advisor® manual Appendix for method of computation. Figure MTT4 shows computations for two examples. Additional values checked against program in Senn, Stephen Cross-over Trials in Clinical Research (2nd Edition) Wiley (2002) and against values computed by MTT0.

Figure MTT4. In the first column, nQuery Advisor® 7.0 computed power, in the second column nQuery Advisor® 7.0 computed n.