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Examples

Creating a Randomization List for a Simple Study
For assigning subjects to groups
This option is for simple designs with 2 to 20 treatments/groups to which subjects must be assigned. Use this option if: …Read More
Complex Design Randomization
This option is for complex designs with multiple treatments, groups, centers and stratifying factors…Read More
Epidemiology Example
Sample Size for Confidence interval for odds ratio
What sample size is required for an experiment to estimate an odds ratio with a confidence interval of specified width?…Read More
Oncology Example
Sample Size for survival analysis
What sample size is required for a study to have 90% power for a comparison of two year survival after surgery for a brain tumor for patients treated with a new combination of chemotherapy and radiation versus those treated with standard methods?…Read More
Second Oncology Example
Sample Size for non-inferiority for survival studies
Many cancer drugs although effective in prolonging survival put patients at considerable risk for serious adverse events. A new drug with an improved safety profile would be of interest even if it did not increase survival as long as survival was not decreased…Read More
DNA Microarray Example
Sample Size for t-test for fold change
For the first time, planners of DNA Microarray studies can easily figure out what sample size will be needed to detect specific fold-changes using a specified p-value…Read More
Genetics Example
Sample Size for Analysis of Variance with unequal n’s
Does a candidate gene influence impaired glucose tolerance in a specified population thought to be susceptible to diabetes?…Read More
Pharmacology Example
Sample Size for Contrast in ANOVA
What sample size is required for an experiment to determine the nature of a dose response to a new drug?…Read More
Psychology Example
Sample Size for Two-way ANOVA
What sample size is required for an experiment in which the effects on a dependent learning variable of age at two levels, nature of contingency reinforcement at four levels and their interaction will be studied?…Read More
Bioequivalence Example
Sample Size for TOST for means-crossover
What sample size is required for a 2×2 crossover study to have 90% power for establishment of equivalence between the 32 hour AUC of two different dosage forms of a drug?…Read More
Dental Research Example
Sample Size for Equivalence of Proportions
What sample size is required for a study comparing a new type of dental implant to a reference standard?…Read More

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