Application Example

This section features 9 detailed examples of how nQuery Advisor can be used for sample size and power calculation in different research scenarios. The examples include:

• DNA Microarray: Testing fold-change with fold-change threshold
• Oncology: Survival analysis
• Psychology: Two-way ANOVA
• Genetics: One-way ANOVA with unequal n’s
• Epidemiology: Confidence interval for odds ratio
• Cardiology: Confidence interval for interclass kappa
• Pharmacology: Contrast in ANOVA
• Dental Research: Non-inferiority tests for proportions
• Bioequivalence: TOST for ratio of means in crossover study

Each application example looks at typical sample size calculation issues that might arise in that particular field of study and goes on to show how nQuery Advisor can be used to resolve these issues.