Statistical Solutions Autumn Newsletter

JSM Miami / ISI Dublin 2011
 This Summer, Statistical Solutions exhibited at two of the largest statistical conferences of the year, JSM Miami, July 31-August 4th and ISI Dublin August 21-26th. At each event we got the opportunity to showcase our great products, hear feedback from existing users and meet up with many old friends.
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Mary Byrne CEO Statistical Solutions and Prof. Donald B. Rubin, Harvard University at the recent ISI conference in Dublin



Brand New Multiple Imputation Method
 SOLAS 4.0 now features a new and unique method to impute missing values. The new method known as the Propensity Score / Predictive Mean / Mahalanobis Distance Combination Method was originally proposed to us by Prof. Donald B. Rubin, the inventor of multiple imputation. The SOLAS implementation of this method was subsequently developed with guidance from Prof. Rubin.
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Click HERE to view a video tutorial on Propensity Score/Predictive Mean/Mahalanobis Distance Combination Method



Cluster Analysis with BMDP
 BMDP provides in-depth functionality for all the major statistical analyses; such as ANOVA, Regression, Nonparametric Analysis, Times Series, etc. Read the following example on how BMDP uses program 1M to perform a Cluster Analysis on market research data.

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Sample Size for TOST for means-crossover
 What sample size is required for a 2×2 crossover study to have 90% power for establishment of equivalence between the 32 hour AUC of two different dosage forms of a drug? Bioequivalence limits will be established for the ratio of the means and the data are expected to have a reasonably normal distribution in the original scale, so the Sasabuchi two one-sided t-tests procedure (TOST) will be used for analysis.
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Statistical Significance and Clinical Relevance: A Contradiction?
The most convincing way to establish efficacy of a new investigational treatment is to demonstrate clinically significant superiority to a concurrent placebo group.
Read a specially commissioned essay by Prof. Dr. Dieter Hauschke, senior statistician and scientist at University Medical School Freiburg.
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Software Trials, Video Tutorial and more:


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Europe
Tel:+ 353 21 4849085     Email : sales@statsol.ie Website : www.statsol.ie

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Tel: 1800-262 1171     Email : info@statsolusa.com Website : www.statsolusa.com

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