Statistical Solutions Newsletter

ASC Bristol Report by Andrew Grannell
Andrew Granell and Eoghan Murphy travelled to Bristol in September to attend the Association of Survey Computing meeting. The two day event included presentations from many well know speakers including Andrew’s presentation on using multiple imputation to adjust for survey non-response.
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Andrew Grannell at the ASC meeting in Bristol

FDA Guidelines For Handling Missing Data in Clinical Trials
At the request of FDA, the National Research Council convened the Panel on the Handling of Missing Data in Clinical Trials, under the Committee on National Statistics, to prepare “a report with recommendations that would be useful for FDA’s development of a guidance for clinical trials on appropriate study designs and follow-up methods to reduce missing data and appropriate statistical methods to address missing data for analysis of results.
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Boolean Factor Analysis

BMDP is the only statistical software package that performs Boolean Factor Analysis. BMDP Program 8M estimates Boolean factors of dichotomous (binary) data. The following example performs a Boolean factor analysis on a study of lymphocyte blood cells of 50 patients tested with a panel of 20 reagent antisera (vaccines).
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2 means example using the Pocock Spending Function

A study is being carried out to compare two-year survival after surgery for a brain tumour for patients treated with a new combination of chemotherapy and radiation, versus those treated with standard methods.
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Free Upcoming Webinars


Statistical Solutions will present the following Webinars in December 2011.

  • Tuesday 6th December  10AM – 11AM  GMT
    Multiple Imputation In Pharmaceutical Clinical Trials Using SOLAS Missing Data Analysis
    Click HERE to register
  • Wednesday 7th December 2PM – 3PM EST
    Multiple Imputation for Pharmaceutical Clinical Trials Using SOLAS Missing Data Analysis
    Click HERE to register

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